Ummahan Rumeysa Rüzgar1, Mehmet Mazhar Çelikoyar2

1Demiroğlu Bilim University, Faculty of Medicine, Istanbul, Turkey
2Department of Otolaryngology, Istanbul Florence Nightingale Hospital, Istanbul, Turkey

Keywords: Head and neck cancer, larynx cancer, oral cavity cancer, second primary malignancy, squamous cell carcinoma

Abstract

Head and neck cancer represents the sixth most common cancer in the world. Men are affected two to three times more than women, possibly as a result of higher tobacco and alcohol consumption. Oral cavity tumors have the highest rate of developing second primary malignancies. In patients with malignancies associated with alcohol and tobacco consumption, 80% of second primary tumors appear in the oral cavity, oropharynx, and larynx. Second primary tumors are usually invasive in nature with early metastasis and should be treated with aggressive therapy. Herein, we report a rare case of a second primary cancer in the larynx after a gingival squamous cell carcinoma.