Ummahan Rumeysa Rüzgar1, Mehmet Mazhar Çelikoyar2

1Demiroğlu Bilim University, Faculty of Medicine, Istanbul, Turkey
2Department of Otolaryngology, Istanbul Florence Nightingale Hospital, Istanbul, Turkey

Keywords: Head and neck cancer, larynx cancer, oral cavity cancer, second primary malignancy, squamous cell carcinoma


Head and neck cancer represents the sixth most common cancer in the world. Men are affected two to three times more than women, possibly as a result of higher tobacco and alcohol consumption. Oral cavity tumors have the highest rate of developing second primary malignancies. In patients with malignancies associated with alcohol and tobacco consumption, 80% of second primary tumors appear in the oral cavity, oropharynx, and larynx. Second primary tumors are usually invasive in nature with early metastasis and should be treated with aggressive therapy. Herein, we report a rare case of a second primary cancer in the larynx after a gingival squamous cell carcinoma.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.