İbrahim Halil Sever1, Tural Mammadov2, Nagihan İnan Gürcan1, Yıldıray Yüzer3

1Department of Radiology, Demiroglu Bilim University, Istanbul, Turkey
2Department of Radiology, Istanbul Florence Nightingale Hospital, Istanbul, Turkey
3Department of General Surgery and Liver Transplantation, Istanbul Florence Nightingale Hospital, Istanbul, Turkey

Keywords: Colon, hepatocellular carcinoma, metastasis, portal hypertension, transcatheter arterial radioembolization


Hematogenous metastasis of hepatocellular carcinoma (HCC), particularly to colon is extremely rare. We presented two cases of colonic metastasis of HCC to the sigmoid colon and rectum. We followed the first patient for six years with chemotherapy, transcatheter arterial radioembolization (four times), and surgical treatment. Liver transplantation was planned because of the patient’s infiltrative HCC in the liver, with no extrahepatic metastasis. Unfortunately, the patient died after the five-year follow-up. The second patient, who was followed for nine years with surgical treatment and chemotherapy, presented with hepatic mass caused by hepatitis B infection. The patient is still in follow-up with multiple peritoneal implants.