Restless leg syndrome developing due to usage of mirtazapine and paroxetine

Abstract

Restless leg syndrome (RLS) is an illness of which its ethiopathogenesis is not known clearly, frequency has been increasing gradually in recent years, and which impairs the quality of life by affecting the sleep pattern severely. In this study, we present RLS cases which developed due to usage of antidepressant medicines. Restless leg syndrome developed after paroxetine and mirtazapine treatments which had been started due to different reasons in two female patients aged 32 and 56 who had no previous complaints. Since no risk factors were detected in both patients after differential diagnoses, patients were diagnosed as RLS developing due to antidepressant usage. Patients’ complaints ended after these treatments were ceased. Frequency of usage of antidepressant medicines has been increasing gradually. As a result, RLS which may be caused by these medicines should be taken into consideration.