İsmail Polat Canbolat1, Alev Arat-Özkan2

1Department of Cardiology, Demiroglu Bilim University Faculty of Medicine, Istanbul, Turkey
2Department of Cardiology, Istanbul University Cerrahpaşa Faculty of Medicine, Istanbul, Turkey

Keywords: Bare-metal stent, drug-eluting stent, in-stent restenosis


Objectives: Clinical, angiographic, and biochemical factors associated with in-stent restenosis were retrospectively analyzed in patients undergoing percutaneous coronary intervention.

Materials and methods: Patients who had undergone follow-up angiography for de novo lesions six months after bare metal stent (BMS) and nine months after drug eluting stent (DES) implantation were retrospectively analyzed. Demographic, angiographic, and clinical parameters were collected from our patient database: In-stent restenosis (ISR) was defined as >50% narrowing of stent lumen or coronary artery 5 mm adjacent to stent edges. Retrospectively 319 patients with a mean age of 57.6 years were included in this study.

Results: In-stent restenosis occurred in 26.6% of the patients with drug-eluting stent and 36.5% of the patients with bare-metal stent implanted. Tobacco use was significantly more frequent among patients with in-stent restenosis.

Conclusion: In-stent restenosis rates in our study is consistent with the literature. Studies are ongoing to overcome this challenging problem.

Conflict of Interest

The authors declared no conflicts of interest with respect to the authorship and/or publication of this article.

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.