Comparison of clinicopathological and demographic features of early and late phase gastric cancer patients

Abstract

Objectives: Comparison of clinicopathological and demographic features of early and late stage gastric cancer patients and determination of prog- nostic factors that specific for late stage patients.
Patients and methods: Files of 145 patients diagnosed with adenocarcinoma, operated at Zonguldak Karaelmas University School of Medicine Training and Research Hospital were examined retrospectively.
Results: There were 19 early-stage patient. Lymph node involvement of two patients was positive. Three patients had been died non-cancer related causes. Average follow-up time was 58.7 months for 16 patient. Average survey of late stage patients were 26.10 months. The factors that affect survey statistically significant were determined as age, T-N score and number of lymph node that removed. Prognostic factors that specific to the stages were examined: age and lymph node number that removed for stage 2, age, macroscopic image, taking chemotherapy, size and differentiation degree for stage 3, size for stage 4 was determined as a factors that effect to survey.
Conclusion: In our study, depth of invasion was associated with lymph node positivity in early stage. The detection of number of lymph node resec- tion as a prognostic factor in late stage might be due to insufficient lymph node dissection to 46 of 126 patients. Lack of statistical difference in terms of survey between stages 3-4 may be due to incorrect staging because of lower lymph node removal in stage 3 than stage 4 and extension of survey because of removal of more lymph nodes in stage 4.