Ezgi Hasbek1, Emine Kübra Dindar Demiray2, Sevil Alkan3, Metin Hüseyin Metineren4

1Department of Pediatrics Clinic, Bitlis State Hospital, Bitlis, Türkiye
2Department of Infectious Disease, Bitlis State Hospital, Bitlis, Türkiye
3Department of Infectious Disease, Çanakkale Onsekiz Mart University, Çanakkale, Türkiye
4Department of Pathology, Kütahya Health Sciences University, Evliya Çelebi Hospital, Kütahya, Türkiye

Keywords: Childhood, local side effects, subcutaneous tissue infection, DT & Td vaccine, DTaP & Tdap


Vaccines are the most economical and effective method applied to protect the health of society and the individual. The extended vaccination program and our national immunization calendar in the eighth grade diphtheria-tetanus (DT & Td) vaccine adult-type are also used in this context. Tetanus immunization is administered in the form of adult DT & Td after the age of 7-10 years. Since diphtheria toxoid is less in amount, it has fewer side effects compared to diphtheria, tetanus, and pertussis (DTaP & Tdap) and DT & Td vaccines at this age. However, local skin infection is observed in one out of every four people following vaccination applications, but there may be rare cases that progress to severe soft tissue infections. With this case, we reported a rare case of DT & Td vaccination-associated deep wound infection in the skin and subcutaneous tissues that was admitted to a pediatric outpatient clinic.

Cite this article as: Hasbek E, Dindar Demiray EK, Alkan S, Metineren MH.Fat and skin necrosis: A rare adverse event in a child due to Tetanus and Diphtheria Vaccine. D J Med Sci 2023;9(1):19-23. doi: 10.5606/fng.btd.2023.34.

Conflict of Interest

Declaration of conflicting interests

Financial Disclosure

The authors received no financial support for the research and/or authorship of this article.